PATENTS/PUBLICATIONS

RD – NÉPHROLOGIE has filed patents on technological advances in the medical field. RD – NÉPHROLOGIE publishes results in peer-reviewed scientific journals and as a poster at scientific conferences. Two PhDs have been successfully conducted under the supervision of Angel Argilés.


PATENTS

WO2022152795 – CYCLIC OXAPHOSPHINANE COMPOUNDS AND ANALOGUES THEREOF FOR TREATING FIBROTIC DISEASES

WO2022136437 – PEPTIDES FOR PREVENTING OR TREATING HEART AND BLOOD VESSEL DISEASES

EP2910261 – METHOD TO CONTROL A DEVICE FOR BLOOD TREATMENT

EP2362790 – APPARATUS FOR EXTRACORPOREAL BLOOD TREATMENT

EP2493525 – DEVICE AND METHOD FOR CHARACTERIZING AN EXTRACORPOREAL BLOOD TREATMENT, AND EXTRACORPOREAL TREATMENT APPARATUS IMPLEMENTING SUCH A DEVICE


PUBLICATIONS

Vascular calcification in different arterial beds in ex vivo ring culture and in vivo rat model.
Muyor K, Laget J, Cortijo I, Duranton F, Jover B, Argilés À, Gayrard N.
Sci Rep. 2022 Jul 13;12(1):11861. doi: 10.1038/s41598-022-15739-w.
PMID:35831341
71
Renal insufficiency and chronic kidney disease – Promotor or consequence of pathological post-translational modifications.
Laget J, Duranton F, Argilés À, Gayrard N.
Mol Aspects Med. 2022 Feb 10:101082. doi: 10.1016/j.mam.2022.101082. Online ahead of print.
PMID:35153062
70
Optimization of RNA extraction methods from human metabolic tissue samples of the COMET biobank.
Nouvel A, Laget J, Duranton F, Leroy J, Desmetz C, Servais MD, de Préville N, Galtier F, Nocca D, Builles N, Rebuffat S, Lajoix AD.
Sci Rep. 2021 Oct 25;11(1):20975. doi: 10.1038/s41598-021-00355-x.
PMID: 34697345
69
Prevention of vascular calcification by the endogenous chromogranin A-derived mediator that inhibits osteogenic transdifferentiation.
Orth-Alampour S, Gayrard N, Salem S, Bhargava S, Jankowski V, Jover B, Notarnicola C, Noels H, van der Vorst EPC, Kuppe C, Wolf M, Goettsch C, Theelen W, Bruck H, Fliser D, Loscalzo J, Wu Z, Marx N, Zidek W, Argilés À, Jankowski J.
Basic Res Cardiol. 2021 Oct 13;116(1):57. doi: 10.1007/s00395-021-00899-z.
PMID: 34647168
68
Effects of high-fat diets on inflammation and antioxidant status in rats : comparison between palm olein and olive oil.
Djohan YF, Monde AA, Camara-Cissé M, Badia E, Bonafos B, Fouret G, Lauret C, Dupuy AM, Pinot E, Koffi G, Niamké G, Sutra T, Gaillet S, Lambert K, Raynaud F, Gayrard N, Jover B, Cristol JP, Coudray C, Feillet-Coudray C.
Acta Biochim Pol. 2021 Oct 6. doi: 10.18388/abp.2020_5639. Online ahead of print.
PMID: 34614344
67
A history of uraemic toxicity and of the European Uraemic Toxin Work Group (EUTox).
Vanholder R, Argilés A, Jankowski J; European Uraemic Toxin Work Group (EUTox).
Clin Kidney J. 2021 Jan 24;14(6):1514-1523. doi: 10.1093/ckj/sfab011. eCollection 2021 Jun.
PMID: 34413975 Free PMC article.
66
The renal patient seen by non-renal physicians: the kidney embedded in the ‘milieu intérieur’.
Perez-Villa F, Lafage-Proust MH, Gielen E, Ortiz A, Spasovski G, Argilés À.
Clin Kidney J. 2020 Dec 11;14(4):1077-1087. doi: 10.1093/ckj/sfaa234. eCollection 2021 Apr.
PMID: 34094517 Free PMC article. Review.
65
Peripancreatic Adipose Tissue Remodeling and Inflammation during High Fat Intake of Palm Oils or Lard in Rats.
Laget J, Djohan YF, Jeanson L, Muyor K, Badia E, Cristol JP, Coudray C, Feillet-Coudray C, Vigor C, Oger C, Galano JM, Durand T, Lajoix AD, Gayrard N, Jover B.
Nutrients. 2021 Mar 30;13(4):1134. doi: 10.3390/nu13041134.
PMID: 33808251 Free PMC article.
64
Vitamin D3 Supplementation Alleviates Left Ventricular Dysfunction in a Mouse Model of Diet-Induced Type 2 Diabetes: Potential Involvement of Cardiac Lipotoxicity Modulation.
Philouze C, Martin JC, Riva C, Marziou A, Defoort C, Couturier C, Berton T, Astier J, Jover B, Gayrard N, Reboul C, Gayrard S, Landrier JF, Obert P.
Cardiovasc Drugs Ther. 2021 Mar 4. doi: 10.1007/s10557-021-07143-9. Online ahead of print.
PMID: 33661433
63
Data Sharing Under the General Data Protection Regulation: Time to Harmonize Law and Research Ethics?
Vlahou A, Hallinan D, Apweiler R, Argiles A, Beige J, Benigni A, Bischoff R, Black PC, Boehm F, Céraline J, Chrousos GP, Delles C, Evenepoel P, Fridolin I, Glorieux G, van Gool AJ, Heidegger I, Ioannidis JPA, Jankowski J, Jankowski V, Jeronimo C, Kamat AM, Masereeuw R, Mayer G, Mischak H, Ortiz A, Remuzzi G, Rossing P, Schanstra JP, Schmitz-Dräger BJ, Spasovski G, Staessen JA, Stamatialis D, Stenvinkel P, Wanner C, Williams SB, Zannad F, Zoccali C, Vanholder R.
Hypertension. 2021 Apr;77(4):1029-1035. doi: 10.1161/HYPERTENSIONAHA.120.16340. Epub 2021 Feb 15.
PMID: 33583200 Free PMC article. Review.
62
Home based therapies: can wishes be realized?
Argilés A, Kerr PG.
Nephrol Dial Transplant. 2020 Nov 1;35(11):1836-1839. doi: 10.1093/ndt/gfaa082.
PMID: 33151335 No abstract available.
61
Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients.
Couchoud C, Bayer F, Ayav C, Béchade C, Brunet P, Chantrel F, Frimat L, Galland R, Hourmant M, Laurain E, Lobbedez T, Mercadal L, Moranne O; French REIN registry.
Kidney Int. 2020 Dec;98(6):1519-1529. doi: 10.1016/j.kint.2020.07.042. Epub 2020 Aug 25.
PMID: 32858081 Free PMC article.
60
Multiplexed MRM-based protein quantification of putative prognostic biomarkers for chronic kidney disease progression in plasma.
Makridakis M, Kontostathi G, Petra E, Stroggilos R, Lygirou V, Filip S, Duranton F, Mischak H, Argiles A, Zoidakis J, Vlahou A.
Sci Rep. 2020 Mar 16;10(1):4815. doi: 10.1038/s41598-020-61496-z.
PMID: 32179759 Free PMC article.
59
Optimisation of cell and ex vivo culture conditions to study vascular calcification.
Gayrard N, Muyor K, Notarnicola C, Duranton F, Jover B, Argilés À.
PLoS One. 2020 Mar 6;15(3):e0230201. doi: 10.1371/journal.pone.0230201. eCollection 2020.
PMID: 32143215 Free PMC article.
58
Differential sensitivity of human islets from obese versus lean donors to chronic high glucose or palmitate.
Castex F, Leroy J, Broca C, Mezghenna K, Duranton F, Lavallard V, Lebreton F, Gross R, Wojtusciszyn A, Lajoix AD.
J Diabetes. 2020 Jul;12(7):532-541. doi: 10.1111/1753-0407.13026. Epub 2020 Mar 6.
PMID: 32090456
57
Measuring intradialyser transmembrane and hydrostatic pressures: pitfalls and relevance in haemodialysis and haemodiafiltration.
Ficheux A, Gayrard N, Szwarc I, Duranton F, Vetromile F, Brunet P, Servel MF, Jankowski J, Argilés À.
Clin Kidney J. 2019 Apr 19;13(4):580-586. doi: 10.1093/ckj/sfz033. eCollection 2020 Aug.
PMID: 32905251 Free PMC article.
56
Serum levels of miR-126 and miR-223 and outcomes in chronic kidney disease patients.
Fourdinier O, Schepers E, Metzinger-Le Meuth V, Glorieux G, Liabeuf S, Verbeke F, Vanholder R, Brigant B, Pletinck A, Diouf M, Burtey S, Choukroun G, Massy ZA, Metzinger L; European Uremic Toxin Work Group-EUTox.
Sci Rep. 2019 Mar 14;9(1):4477. doi: 10.1038/s41598-019-41101-8.
PMID: 30872798 Free PMC article.
55
High dietary intake of palm oils compromises glucose tolerance whereas high dietary intake of olive oil compromises liver lipid metabolism and integrity.
Djohan YF, Badia E, Bonafos B, Fouret G, Lauret C, Dupuy AM, Pinot E, Sutra T, Gaillet S, Lambert K, Raynaud F, Gayrard N, Jover B, Monde AA, Cristol JP, Coudray C, Feillet-Coudray C.
Eur J Nutr. 2019 Dec;58(8):3091-3107. doi: 10.1007/s00394-018-1854-3. Epub 2018 Nov 3.
PMID: 30392135
54
Blood Pressure Seasonality in Hemodialysis Patients from Five European Cities of Different Latitudes.
Duranton F, Palma A, Stegmayr B, Wauthier M, Torres A, Argilés À.
Kidney Blood Press Res. 2018;43(5):1529-1538. doi: 10.1159/000494019. Epub 2018 Oct 4.
PMID: 30286451
53
The CKD plasma lipidome varies with disease severity and outcome.
Duranton F, Laget J, Gayrard N, Saulnier-Blache JS, Lundin U, Schanstra JP, Mischak H, Weinberger KM, Servel MF, Argilés A.
J Clin Lipidol. 2019 Jan-Feb;13(1):176-185.e8. doi: 10.1016/j.jacl.2018.07.010. Epub 2018 Aug 1.
PMID: 30177483
52
5-HT2C receptors in the ventral tegmental area, but not in the arcuate nucleus, mediate the hypophagic and hypolocomotor effects of the selective 5-HT2C receptor agonist AR231630 in rats.
Faton S, Tassin JP, Duranton F, Bagnol D, Lajoix AD.
Behav Brain Res. 2018 Jul 16;347:234-241. doi: 10.1016/j.bbr.2018.03.006. Epub 2018 Mar 17.
PMID: 29555337
51
Correction: Consequences of increasing convection onto patient care and protein removal in hemodialysis.
Gayrard N, Ficheux A, Duranton F, Guzman C, Szwarc I, Vetromile F, Cazevieille C, Brunet P, Servel MF, Argilés À, Le Quintrec M.
PLoS One. 2018 Jan 2;13(1):e0190761. doi: 10.1371/journal.pone.0190761. eCollection 2018.
PMID: 29293688 Free PMC article.
50
Geographical Variations in Blood Pressure Level and Seasonality in Hemodialysis Patients.

Duranton F, Kramer A, Szwarc I, Bieber B, Gayrard N, Jover B, Vetromile F, Massy ZA, Combe C, Tentori F, Jager KJ, Servel MF, Argilés À.
Hypertension. 2018 Feb;71(2):289-296. doi: 10.1161/HYPERTENSIONAHA.117.10274. Epub 2017 Dec 18.
PMID: 29255071

49
Is Plasma Proteomics Able to Provide Alternative Paths to Better Understand Hypertension?
Argilés À, Rodriguez M, Ortiz A.
Hypertension. 2017 Aug;70(2):250-252. doi: 10.1161/HYPERTENSIONAHA.117.09049. Epub 2017 Jun 26.
PMID: 28652468 No abstract available.
48
Clinical expectations for the new bioactive treatments: greater well-being or longer survival?
Szwarc I, Vetromile F, Buscaroli A, Françoise Servel M, Argilés À.
Int J Artif Organs. 2017 Jul 5;40(7):335-337. doi: 10.5301/ijao.5000582. Epub 2017 Jun 14.
PMID: 28623641 No abstract available.
47
A reliable method to assess the water permeability of a dialysis system: the global ultrafiltration coefficient.
Ficheux A, Gayrard N, Duranton F, Guzman C, Szwarc I, Vetromile F, Brunet P, Servel MF, Argilés A.
Nephrol Dial Transplant. 2017 Feb 1;32(2):364-370. doi: 10.1093/ndt/gfw370.
PMID: 28186570 Free PMC article.
46
Consequences of increasing convection onto patient care and protein removal in hemodialysis.
Gayrard N, Ficheux A, Duranton F, Guzman C, Szwarc I, Vetromile F, Cazevieille C, Brunet P, Servel MF, Argilés À, Le Quintrec M.
PLoS One. 2017 Feb 6;12(2):e0171179. doi: 10.1371/journal.pone.0171179. eCollection 2017.
PMID: 28166268 Free PMC article.
45
Primary sclerosing cholangitis: a new cause of distal renal tubular acidosis.
Goutaudier V, Szwarc I, Serre JE, Pageaux GP, Argilés À, Ribstein J.
Clin Kidney J. 2016 Dec;9(6):811-813. doi: 10.1093/ckj/sfw085. Epub 2016 Aug 31.
PMID: 27994859 Free PMC article.
44
Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis.
Siwy J, Zürbig P, Argiles A, Beige J, Haubitz M, Jankowski J, Julian BA, Linde PG, Marx D, Mischak H, Mullen W, Novak J, Ortiz A, Persson F, Pontillo C, Rossing P, Rupprecht H, Schanstra JP, Vlahou A, Vanholder R.
Nephrol Dial Transplant. 2017 Dec 1;32(12):2079-2089. doi: 10.1093/ndt/gfw337.
PMID: 27984204 Free PMC article.
43
Relaxin and atrial natriuretic peptide pathways participate in the anti-fibrotic effect of a melon concentrate in spontaneously hypertensive rats.
Carillon J, Gauthier A, Barial S, Tournier M, Gayrard N, Lajoix AD, Jover B.
Food Nutr Res. 2016 Apr 12;60:30985. doi: 10.3402/fnr.v60.30985. eCollection 2016.
PMID: 27079780 Free PMC article.
42
Early changes in body weight and blood pressure are associated with mortality in incident dialysis patients.
Duranton F, Duny Y, Szwarc I, Deleuze S, Rouanet C, Selcer I, Maurice F, Rivory JP, Servel MF, Jover B, Brunet P, Daurès JP, Argilés À.
Clin Kidney J. 2016 Apr;9(2):287-94. doi: 10.1093/ckj/sfv153. Epub 2016 Jan 29.
PMID: 26985382 Free PMC article.
41
On the discovery of UREA. Identification, synthesis and observations that let to establishing the first uraemic retention solute.
Duranton F, Jankowski J, Więcek A, Argilés À.
G Ital Nefrol. 2016 Feb;33 Suppl 66:33.S66.16.
PMID: 26913884
40
The fate of triaged and rejected manuscripts.
Zoccali C, Amodeo D, Argiles A, Arici M, D’arrigo G, Evenepoel P, Fliser D, Fox J, Gesualdo L, Jadoul M, Ketteler M, Malyszko J, Massy Z, Mayer G, Ortiz A, Sever M, Vanholder R, Vinck C, Wanner C, Więcek A.
Nephrol Dial Transplant. 2015 Dec;30(12):1947-50. doi: 10.1093/ndt/gfv387.
PMID: 26597920 Free PMC article.
39
New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis.
Glorieux G, Mullen W, Duranton F, Filip S, Gayrard N, Husi H, Schepers E, Neirynck N, Schanstra JP, Jankowski J, Mischak H, Argilés À, Vanholder R, Vlahou A, Klein J.
Nephrol Dial Transplant. 2015 Nov;30(11):1842-52. doi: 10.1093/ndt/gfv254. Epub 2015 Jul 9.
PMID: 26160894
38
Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides.
Schanstra JP, Zürbig P, Alkhalaf A, Argiles A, Bakker SJ, Beige J, Bilo HJ, Chatzikyrkou C, Dakna M, Dawson J, Delles C, Haller H, Haubitz M, Husi H, Jankowski J, Jerums G, Kleefstra N, Kuznetsova T, Maahs DM, Menne J, Mullen W, Ortiz A, Persson F, Rossing P, Ruggenenti P, Rychlik I, Serra AL, Siwy J, Snell-Bergeon J, Spasovski G, Staessen JA, Vlahou A, Mischak H, Vanholder R.
J Am Soc Nephrol. 2015 Aug;26(8):1999-2010. doi: 10.1681/ASN.2014050423. Epub 2015 Jan 14.
PMID: 25589610 Free PMC article. Clinical Trial.
37
[Preventing chronic kidney disease in France: advantages, feasibility and concerns].
Duranton F, Brunet P, Laville M, Landais P, Daurès JP, Mourad G, Bustins M, Argilés A.
Nephrol Ther. 2014 Dec;10(7):492-9. doi: 10.1016/j.nephro.2014.06.007. Epub 2014 Nov 20.
PMID: 25457993 Review. French.
36
Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease.
Nkuipou-Kenfack E, Duranton F, Gayrard N, Argilés À, Lundin U, Weinberger KM, Dakna M, Delles C, Mullen W, Husi H, Klein J, Koeck T, Zürbig P, Mischak H.
PLoS One. 2014 May 9;9(5):e96955. doi: 10.1371/journal.pone.0096955. eCollection 2014.
PMID: 24817014 Free PMC article.
35
Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy.
Siwy J, Schanstra JP, Argiles A, Bakker SJ, Beige J, Boucek P, Brand K, Delles C, Duranton F, Fernandez-Fernandez B, Jankowski ML, Al Khatib M, Kunt T, Lajer M, Lichtinghagen R, Lindhardt M, Maahs DM, Mischak H, Mullen W, Navis G, Noutsou M, Ortiz A, Persson F, Petrie JR, Roob JM, Rossing P, Ruggenenti P, Rychlik I, Serra AL, Snell-Bergeon J, Spasovski G, Stojceva-Taneva O, Trillini M, von der Leyen H, Winklhofer-Roob BM, Zürbig P, Jankowski J.
Nephrol Dial Transplant. 2014 Aug;29(8):1563-70. doi: 10.1093/ndt/gfu039. Epub 2014 Mar 2.
PMID: 24589724 Free PMC article. Clinical Trial.
34
The Saga of Two Centuries of Urea: Nontoxic Toxin or Vice Versa?
Duranton F, Depner TA, Argilés À.
Semin Nephrol. 2014 Mar;34(2):87-96. doi: 10.1016/j.semnephrol.2014.02.002. Epub 2014 Feb 15.
PMID: 26248717 Review.
33
The ultrafiltration coefficient: this old ‘grand inconnu’ in dialysis.
Ficheux A, Ronco C, Brunet P, Argilés À.
Nephrol Dial Transplant. 2015 Feb;30(2):204-8. doi: 10.1093/ndt/gft493. Epub 2013 Dec 19.
PMID: 24362905 Free PMC article. Review. No abstract available.
32
Plasma and urinary amino acid metabolomic profiling in patients with different levels of kidney function.
Duranton F, Lundin U, Gayrard N, Mischak H, Aparicio M, Mourad G, Daurès JP, Weinberger KM, Argilés A.
Clin J Am Soc Nephrol. 2014 Jan;9(1):37-45. doi: 10.2215/CJN.06000613. Epub 2013 Nov 14.
PMID: 24235289 Free PMC article.
31
Exogenous thyrotropin improves renal function in euthyroid patients, while serum creatinine levels are increased in hypothyroidism.
Duranton F, Lacoste A, Faurous P, Deshayes E, Ribstein J, Avignon A, Mourad G, Argilés À.
Clin Kidney J. 2013 Oct;6(5):478-83. doi: 10.1093/ckj/sft092. Epub 2013 Sep 1.
PMID: 26064512 Free PMC article.
30
CKD273, a new proteomics classifier assessing CKD and its prognosis.
Argilés Á, Siwy J, Duranton F, Gayrard N, Dakna M, Lundin U, Osaba L, Delles C, Mourad G, Weinberger KM, Mischak H.
PLoS One. 2013 May 14;8(5):e62837. doi: 10.1371/journal.pone.0062837. Print 2013.
PMID: 23690958 Free PMC article.
29
Vitamin D treatment and mortality in chronic kidney disease: a systematic review and meta-analysis.
Duranton F, Rodriguez-Ortiz ME, Duny Y, Rodriguez M, Daurès JP, Argilés A.
Am J Nephrol. 2013;37(3):239-48. doi: 10.1159/000346846. Epub 2013 Mar 5.
PMID: 23467111 Review.
28
Normal and pathologic concentrations of uremic toxins.
Duranton F, Cohen G, De Smet R, Rodriguez M, Jankowski J, Vanholder R, Argiles A; European Uremic Toxin Work Group.
J Am Soc Nephrol. 2012 Jul;23(7):1258-70. doi: 10.1681/ASN.2011121175. Epub 2012 May 24.
PMID: 22626821 Free PMC article. Review.
27
Implementation of proteomic biomarkers: making it work.
Mischak H, Ioannidis JP, Argiles A, Attwood TK, Bongcam-Rudloff E, Broenstrup M, Charonis A, Chrousos GP, Delles C, Dominiczak A, Dylag T, Ehrich J, Egido J, Findeisen P, Jankowski J, Johnson RW, Julien BA, Lankisch T, Leung HY, Maahs D, Magni F, Manns MP, Manolis E, Mayer G, Navis G, Novak J, Ortiz A, Persson F, Peter K, Riese HH, Rossing P, Sattar N, Spasovski G, Thongboonkerd V, Vanholder R, Schanstra JP, Vlahou A.
Eur J Clin Invest. 2012 Sep;42(9):1027-36. doi: 10.1111/j.1365-2362.2012.02674.x. Epub 2012 Apr 21.
PMID: 22519700 Free PMC article.
26
Determination of uremic solutes in biological fluids of chronic kidney disease patients by HPLC assay.
Calaf R, Cerini C, Génovésio C, Verhaeghe P, Jourde-Chiche N, Bergé-Lefranc D, Gondouin B, Dou L, Morange S, Argilés A, Rathelot P, Dignat-George F, Brunet P, Charpiot P.
J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Aug 1;879(23):2281-6. doi: 10.1016/j.jchromb.2011.06.014. Epub 2011 Jun 15.
PMID: 21727042
25
Does uremia cause vascular dysfunction?
Brunet P, Gondouin B, Duval-Sabatier A, Dou L, Cerini C, Dignat-George F, Jourde-Chiche N, Argiles A, Burtey S.
Kidney Blood Press Res. 2011;34(4):284-90. doi: 10.1159/000327131. Epub 2011 Jun 21.
PMID: 21691132 Review.
24
The use of SDS-PAGE scanning of spent dialysate to assess uraemic toxin removal by dialysis.
Ficheux A, Gayrard N, Szwarc I, Andress D, Soullier S, Duny Y, Goubert G, Thomas M, Bismuth-Mondolfo J, Daurès JP, Brunet P, Servel MF, Argilés A.
Nephrol Dial Transplant. 2011 Jul;26(7):2281-9. doi: 10.1093/ndt/gfq709. Epub 2010 Dec 10.
PMID: 21148683 Free PMC article. Clinical Trial.
23
Guanidino compounds as cause of cardiovascular damage in chronic kidney disease: an in vitro evaluation.
Schepers E, Glorieux G, Dou L, Cerini C, Gayrard N, Louvet L, Maugard C, Preus P, Rodriguez-Ortiz M, Argiles A, Brunet P, Cohen G, Jankowski J, Jankowski V, Massy Z, Rodriguez M, Vanholder R; European Uremic Toxin Work Group (EUTox).
Blood Purif. 2010;30(4):277-87. doi: 10.1159/000320765. Epub 2010 Nov 16.
PMID: 21079396
22
Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology.
Maahs DM, Siwy J, Argilés A, Cerna M, Delles C, Dominiczak AF, Gayrard N, Iphöfer A, Jänsch L, Jerums G, Medek K, Mischak H, Navis GJ, Roob JM, Rossing K, Rossing P, Rychlík I, Schiffer E, Schmieder RE, Wascher TC, Winklhofer-Roob BM, Zimmerli LU, Zürbig P, Snell-Bergeon JK.
PLoS One. 2010 Sep 28;5(9):e13051. doi: 10.1371/journal.pone.0013051.
PMID: 20927192 Free PMC article.
21
The ultrafiltration coefficient of a dialyser (KUF) is not a fixed value, and it follows a parabolic function: the new concept of KUF max.
Ficheux A, Kerr PG, Brunet P, Argilés À.
Nephrol Dial Transplant. 2011 Feb;26(2):636-40. doi: 10.1093/ndt/gfq510. Epub 2010 Sep 8.
PMID: 20826740
20
Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease.
Good DM, Zürbig P, Argilés A, Bauer HW, Behrens G, Coon JJ, Dakna M, Decramer S, Delles C, Dominiczak AF, Ehrich JH, Eitner F, Fliser D, Frommberger M, Ganser A, Girolami MA, Golovko I, Gwinner W, Haubitz M, Herget-Rosenthal S, Jankowski J, Jahn H, Jerums G, Julian BA, Kellmann M, Kliem V, Kolch W, Krolewski AS, Luppi M, Massy Z, Melter M, Neusüss C, Novak J, Peter K, Rossing K, Rupprecht H, Schanstra JP, Schiffer E, Stolzenburg JU, Tarnow L, Theodorescu D, Thongboonkerd V, Vanholder R, Weissinger EM, Mischak H, Schmitt-Kopplin P.
Mol Cell Proteomics. 2010 Nov;9(11):2424-37. doi: 10.1074/mcp.M110.001917. Epub 2010 Jul 8.
PMID: 20616184 Free PMC article.
19
[Dialysis quantification: Is it accurate and can we make it simple?].
Ficheux A, Brunet P, Argilés A.
Nephrol Ther. 2010 Nov;6(6):491-3. doi: 10.1016/j.nephro.2010.01.009. Epub 2010 Jun 8.
PMID: 20570585 French. No abstract available.
18
Use of spent dialysate analysis to estimate blood levels of uraemic solutes without blood sampling: urea.
Ficheux A, Gayrard N, Szwarc I, Soullier S, Bismuth-Mondolfo J, Brunet P, Servel MF, Argilés A.
Nephrol Dial Transplant. 2010 Mar;25(3):873-9. doi: 10.1093/ndt/gfp539. Epub 2009 Oct 23.
PMID: 19854847
17
Conservative treatment of the uremic syndrome.
Vanholder R, Argilés A, Beige J, Brunet P, Drüeke TB, Fliser D, Herget-Rosenthal S, Hörl WH, Jörres A, Perna A, Rodriguez-Portillo M, Spasovski G, Stegmayr B, Stenvinkel P, Wanner C, Wiecek A, Massy ZA.
Semin Dial. 2009 Jul-Aug;22(4):449-53. doi: 10.1111/j.1525-139X.2009.00600.x.
PMID: 19709000 Review.
16
The general picture of uremia.
Almeras C, Argilés A.
Semin Dial. 2009 Jul-Aug;22(4):329-33. doi: 10.1111/j.1525-139X.2009.00575.x.
PMID: 19708976 Review.
15
The role of EUTox in uremic toxin research.
Vanholder R, Abou-Deif O, Argiles A, Baurmeister U, Beige J, Brouckaert P, Brunet P, Cohen G, De Deyn PP, Drüeke TB, Fliser D, Glorieux G, Herget-Rosenthal S, Hörl WH, Jankowski J, Jörres A, Massy ZA, Mischak H, Perna AF, Rodriguez-Portillo JM, Spasovski G, Stegmayr BG, Stenvinkel P, Thornalley PJ, Wanner C, Wiecek A.
Semin Dial. 2009 Jul-Aug;22(4):323-8. doi: 10.1111/j.1525-139X.2009.00574.x.
PMID: 19708975
14
Chronic kidney disease-related mineral and bone disorders.
Argilés A, Vanholder R.
Nephron Clin Pract. 2009;112(3):c128-36. doi: 10.1159/000214207. Epub 2009 Apr 24.
PMID: 19390213 Review.
13
Post-conditioning to reduce renal ischaemia/reperfusion injury.
Szwarc I, Mourad G, Argiles A.
Nephrol Dial Transplant. 2009 Jul;24(7):2288-9; author reply 2289-90. doi: 10.1093/ndt/gfn663. Epub 2009 Apr 1.
PMID: 19339341 No abstract available.
12
The use of online clearances in dialysis.
Argilés A, Ficheux A.
Kidney Int. 2008 Sep;74(6):829; author reply 829-30. doi: 10.1038/ki.2008.273.
PMID: 18756308 No abstract available.
11
Cytogenetic studies of 24 renal epithelial tumors with von Hippel-Lindau and fragile histidine triad protein expression correlation.
Gayrard N, Cacheux V, Iborra F, Mourad G, Argilés A.
Arch Pathol Lab Med. 2008 Jun;132(6):965-73. doi: 10.5858/2008-132-965-CSORET.
PMID: 18517280
10
Ischemic postconditioning prevents ischemic acute renal failure.
Szwarc I, Soullier S, Gayrard N, Mejean C, Mourad G, Argiles A.
Transplant Proc. 2007 Oct;39(8):2554-6. doi: 10.1016/j.transproceed.2007.08.026.
PMID: 17954171
9
Review on uraemic toxins III: recommendations for handling uraemic retention solutes in vitro–towards a standardized approach for research on uraemia.
Cohen G, Glorieux G, Thornalley P, Schepers E, Meert N, Jankowski J, Jankowski V, Argiles A, Anderstam B, Brunet P, Cerini C, Dou L, Deppisch R, Marescau B, Massy Z, Perna A, Raupachova J, Rodriguez M, Stegmayr B, Vanholder R, Hörl WH; European Uremic Toxin Work Group (EUTox).
Nephrol Dial Transplant. 2007 Dec;22(12):3381-90. doi: 10.1093/ndt/gfm210. Epub 2007 Aug 27.
PMID: 17724037 Review. No abstract available.
8
Inconsistency of reported uremic toxin concentrations.
Meert N, Schepers E, De Smet R, Argiles A, Cohen G, Deppisch R, Drüeke T, Massy Z, Spasovski G, Stegmayr B, Zidek W, Jankowski J, Vanholder R.
Artif Organs. 2007 Aug;31(8):600-11. doi: 10.1111/j.1525-1594.2007.00434.x.
PMID: 17651115 Review.
7
Review on uraemic solutes II–variability in reported concentrations: causes and consequences.
Vanholder R, Meert N, Schepers E, Glorieux G, Argiles A, Brunet P, Cohen G, Drüeke T, Mischak H, Spasovski G, Massy Z, Jankowski J; European Uremic Toxin Work Group (EUTox).
Nephrol Dial Transplant. 2007 Nov;22(11):3115-21. doi: 10.1093/ndt/gfm151. Epub 2007 Jun 5.
PMID: 17550927 Review.6
6
Advances in urinary proteome analysis and biomarker discovery.
Fliser D, Novak J, Thongboonkerd V, Argilés A, Jankowski V, Girolami MA, Jankowski J, Mischak H.
J Am Soc Nephrol. 2007 Apr;18(4):1057-71. doi: 10.1681/ASN.2006090956. Epub 2007 Feb 28.
PMID: 17329573 Review.
5
Cinacalcet chloride is efficient and safe in renal transplant recipients with posttransplant hyperparathyroidism.
Szwarc I, Argilés A, Garrigue V, Delmas S, Chong G, Deleuze S, Mourad G.
Transplantation. 2006 Sep 15;82(5):675-80. doi: 10.1097/01.tp.0000232452.80018.ad.
PMID: 16969292
4
[Molecular mechanisms involved in kidney ischemia-reperfusion].
Soullier S, Gayrard N, Méjean C, Swarcz I, Mourad G, Argilés A.
Nephrol Ther. 2005 Nov;1(5):315-21. doi: 10.1016/j.nephro.2005.05.005. Epub 2005 Aug 31.
PMID: 16895701 Review. French.
3
Comprehensive analysis of the renal transcriptional response to acute uranyl nitrate exposure.
Taulan M, Paquet F, Argiles A, Demaille J, Romey MC.
BMC Genomics. 2006 Jan 11;7:2. doi: 10.1186/1471-2164-7-2.
PMID: 16405725 Free PMC article.
2
Chronic kidney disease as cause of cardiovascular morbidity and mortality.
Vanholder R, Massy Z, Argiles A, Spasovski G, Verbeke F, Lameire N; European Uremic Toxin Work Group.
Nephrol Dial Transplant. 2005 Jun;20(6):1048-56. doi: 10.1093/ndt/gfh813. Epub 2005 Apr 6.
PMID: 15814534 Review.
1

POSTERS / SESSIONS

Automatic KUF Max Determination as a Tool to Prescribe a Personalized Convection Flow in Post-Dilution Haemodiafiltration by Predicting the Transmembrane Pressure to Which the System will be Subjected. Alain Ficheux, Jonas Laget, Flore Duranton, Nathalie Gayrard, Fernando Vetromille, Ilan Szwarc, Marie-Françoise Servel, Angel Argiles Ciscart. Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022, gfac077.014, https://doi.org/10.1093/ndt/gfac077.014 (ERA-EDTA 2022, Paris)

Accumulation of REG-1Α in Proximal Tubules of a Rat Model of Chronic Kidney Disease: A New Biomarker at the Interface Between Renal Impairment and Neurodegenerative Diseases. Irene Cortijo, Karen Muyor, Jonas Laget, Bernard Jover, Fabrice Reynaud, Flore Duranton, Pascaline Fontès, Françoise Trousse, Anne Marcilhac, Nadine Mestre-Francés, Angel Argiles Ciscart, Nathalie Gayrard. Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022, gfac070.057, https://doi.org/10.1093/ndt/gfac070.057 (ERA-EDTA 2022, Paris)

PST3.1A, An Inhibitor of MGAT5 Decreases Renal Fibrosis in a Rat Model of Chronic Kidney Disease. Karen Muyor, Jonas Laget, Flore Duranton, Bernard Jover, Irene Cortijo, Séverine Loiseau, Karine Chorro, Carine Jacquard, Bernard Pau, Ludovic Clarion, Angel Argiles Ciscart, Nathalie Gayrard. Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022, gfac063.024, https://doi.org/10.1093/ndt/gfac063.024 (ERA-EDTA 2022, Paris)

Cafeteria Diet-Induced Obesity Worsens Experimental CKD. Karen Muyor, Flore Duranton, Irene Cortijo, Jonas Laget, Bernard Jover, Anne Dominique Lajoix, Angel Argiles Ciscart, Nathalie Gayrard. Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022, gfac074.028, https://doi.org/10.1093/ndt/gfac074.028 (ERA-EDTA 2022, Paris)

Chronic Kidney Disease and Vascular Calcification Result in Inflammation and Dysfunction of Colon Tissue in Rats. Piotr Bartochowski, Karen Muyor, Jonas Laget, Irene Cortijo, Laura Castel, Flore Duranton, Stéphanie Bornes, Angel Argiles Ciscart, Bernard Jover, Magali Cordaillat – Simmons, Nathalie Gayrard. Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022, gfac073.013, https://doi.org/10.1093/ndt/gfac073.013 (ERA-EDTA 2022, Paris)

Characterization of Adrenal Gland Derived Mediators of Vascular Calcification. Shruti Bhargava, Setareh Orth-Alampour, Nathalie Gayrard, Angel Argiles Ciscart, Joachim Jankowski. Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022, gfac070.073, https://doi.org/10.1093/ndt/gfac070.073 (ERA-EDTA 2022, Paris)

Prevention of Vascular Calcification by the Endogenous Chromogranin a-Derived Mediator that Inhibits Osteogenic Transdifferentiation. Joachim Jankowski, Setareh Orth-Alampour, Vera Jankowski, Angel Argiles Ciscart, Nathalie Gayrard. Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022, gfac079.036, https://doi.org/10.1093/ndt/gfac079.036 (ERA-EDTA 2022, Paris)

Increased Senescent Cell Burden and Alterations in NRF2 Pathway Drive Uraemic Vascular Calcification in Humans. Sam Hobson, Jonas Laget, Karen Muyor, Irene Cortijo, Piotr Bartochowski, Bernard Jover, Anne Dominique Lajoix, Thomas Ebert, Peter Stenvinkel, Angel Argiles Ciscart, Nathalie Gayrard, Karolina Kublickiene. Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022, gfac070.068, https://doi.org/10.1093/ndt/gfac070.068 (ERA-EDTA 2022, Paris)

Vascular Cells Senescence and Modifications in NRF2 Pathway in a Model of URaEMIC Vascular Calcification. Jonas Laget, Sam Hobson, Karen Muyor, Flore Duranton, Irene Cortijo, Piotr Bartochowski, Bernard Jover, Anne Dominique Lajoix, Peter Stenvinkel, Angel Argiles Ciscart, Karolina Kublickiene, Nathalie Gayrard. Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022, gfac073.014, https://doi.org/10.1093/ndt/gfac073.014 (ERA-EDTA 2022, Paris)

MODIFICATION OF P16, P21 AND NRF2 EXPRESSION IN A MODEL OF UREMIC VASCULAR CALCIFICATION. Jonas Laget, Sam Hobson, Bernard Jover, Karen Muyor, Flore Duranton, Karolina Kublickiene, Anne Dominique Lajoix, Peter Stenvinkel, Angel Argiles Ciscart, Nathalie Gayrard. Nephrology Dialysis Transplantation, Volume 35, Issue Supplement_3, June 2020, gfaa140.MO056. (ERA-EDTA 2020, Virtual Meeting)

Comparison Of The Performances Of Three Creatinine Clearance Estimation Formulas. Flore Duranton, Nathalie Gayrard, Alain Ficheux, Ilan Szwarc, Fernando Vetromile, Marie-Francoise Servel, Angel Argiles. Nephrology Dialysis Transplantation, Volume 34, Issue Supplement_1, June 2019, gfz103.SP288. (ERA-EDTA 2019, Budapest)

Influence Of Metabolic Syndrome In A 5/6 Nephrectomy Rat Model Of Chronic Kidney Disease. Nathalie Gayrard, Karen Muyor, Bernard Jover, Flore Duranton, Anne-Dominique Lajoix, Angel Argiles. Nephrology Dialysis Transplantation, Volume 34, Issue Supplement_1, June 2019, gfz103.SP399.(ERA-EDTA 2019, Budapest)

Intradialyser Pressures: Limits, Measurement Pitfalls And Influence Of Surface Area. Ficheux A, Gayrard N, Szwarc I, Duranton F, Vetromile F, Brunet P, et al. Nephrol Dial Transplant. 2017 May 1;32(suppl_3):iii283–iii283. (ERA-EDTA 2017, Madrid)

Plasma Lipidomics In Chronic Kidney Disease And Hemodialysis Patients. Flore Duranton, Nathalie Gayrard, Alain Ficheux, Anne-Dominique Lajoix, Klaus M. Weinberger, Harald Mischak, Angel Argiles. Nephrology Dialysis Transplantation, Volume 32, Issue suppl 3, 1 May 2017, Pages iii197–iii198. (ERA-EDTA 2017, Madrid)

Comparative Calcification Rate Of Rat Arteries In Calcification Medium Ex-Vivo: Effect Of Lesion And Section. Nathalie Gayrard, Bernard Jover, Laura Jeanson, Anne-Dominique Lajoix, Flore Duranton, Alain Ficheux, Angel Argiles. Nephrology Dialysis Transplantation, Volume 32, Issue suppl_3, 1 May 2017, Pages iii549. (ERA-EDTA 2017, Madrid)

Influence Of Glucose Metabolism Dysregulation On Ex Vivo Aortic Calcification In Rats. Bernard Jover, Anne-Dominique Lajoix, Flore Duranton, Alain Ficheux, Angel Argiles, Nathalie Gayrard. Nephrology Dialysis Transplantation, Volume 32, Issue suppl_3, 1 May 2017, Pages iii612. (ERA-EDTA 2017, Madrid)

Peripancreatic And Periaortic Adipose Tissues And Obesogenic Diet: Comparison Between Palm And Olive Oil In The Rat. Youzan Ferdinand Djohan, Eric Badia, Charles Coudray, Christine Feillet-Coudray, Anne-Dominique Lajoix, Jean Paul Cristol, Angel Argiles, Nathalie Gayrard, Bernard Jover, Jonas Laget. (SFD 2017, Lille)

Geographical and Seasonal Patterns of Blood Pressure in Hemodialysis Patients: a EURODOPPS Study. Flore Duranton, Anneke Kramer, Brian Bieber, Ziad Massy, Christian Combe, Francesca Tentori, Kitty J. Jager and Angel Argiles. (ASN 2016, Chicago)

Phenotypic remodeling of perivascular adipose tissue in a rat model of metabolic syndrome: vascular consequences and beneficial impact of exercise training. Cindy Meziat, Doria Boulgobhra, Alessandro Do Nascimento, Eva Strock, Sylvain Battault, Gregory Meyer, Sandrine Gayrard, Nathalie Gayrard, Bernard Jover, Guillaume Walther, Cyril Reboul. Archives of Cardiovascular Diseases Supplements, 2016, vol. 8, no 3, p. 213. (Printemps de la Cardiologie 2016, Paris)

Low Blood Pressure And Marked Weight Loss In Incident Dialysis Patients Are Associated With High Mortality. Flore Duranton, Yohan Duny, Ilan Szwarc, Sébastien Deleuze, Catherine Rouanet, Isabelle Selcer, François Maurice, Jean-Pierre Rivory, Bernard Jover, Marie-Françoise Servel, Philippe Brunet, Jean-Pierre Daurès, Angel Argilés. Nephrology Dialysis Transplantation, Volume: 30, Supplement: 3, Meeting Abstract: FP699, Published: MAY 2015. (ERA-EDTA 2015, London)

High-Resolution Plasma Proteome Analysis Identifies New Changes In Molecular Mechanisms Involved In Chronic Kidney Disease. Glorieux Griet, Mullen William, Duranton Flore, Filip Szymon, Gayrard Nathalie, Husi Holger, Schepers Eva, Neirynck Nathalie, Schanstra Joost, Vlahou Antonia, Jankowski Joachim, Mischak Harald, Argiles Angel, Vanholder Raymond, Klein Julie Nephrology Dialysis Transplantation, Volume: 30, Supplement: 3, Meeting Abstract: FP279, Published: MAY 2015. (ERA-EDTA 2015, London)

A reliable method to assess the water permeability of a dialysis system: The global ultrafiltration coefficient. Argilés A, Gayrard N, Duranton F, Guzman C, Szwarc I, Brunet P, Ficheux A. (ASN 2014, Philadelphia)

High convection volumes in on-line haemodiafiltration: Do we know what we prescribe? Ficheux A, Gayrard N, Duranton F, Guzman C, Argilés A. (ASN 2014, Philadelphia)

Early Changes in Systolic Blood Pressure and Body Weight are Associated with Long Term Mortality in Incident Dialysis Patients. F Duranton, Y Duny, I Szwarc, S Deleuze, C Rouanet, I Selcer, F Maurice, JP Rivory, JP Daurès, A Argilés. (ASN 2014, Philadelphia)

Surface, a parameter to consider in high convection volume HDF. Ficheux A, Gayrard N, Duranton F, Guzman C, Szwarc I, Bismuth-Mondolfo J, Brunet P, Servel MF, Argilés A. Nephrology Dialysis Transplantation, Volume: 29, Supplement: 3, Pages: 210-211, Meeting Abstract: SP414, Published: MAY 2014. (ERA-EDTA 2014, Amsterdam)

Calcification aortique ex-vivo : susceptibilité en fonction du dérèglement glucidique chez le rat. B. Jover, S. Rebuffat, A.D. Lajoix, A. Argilés, S. Péraldi-Roux, N. Gayrard. Annales de cardiologie et d’angéiologie 63 (2014), p. 49-50. Référence P-60. (SFHTA 2014, Paris)

Calcification aortique ex vivo: susceptibilité en fonction du dérèglement glucidique chez le rat. N.Gayrard, C. Guzman, M. Tournier, S.Rebuffat, R. Gomis, A-D Lajoix, A. Argilès, S. Péraldi-Roux, B. Jover. Diabetes & Metabolism, 2014, vol. 40, p. A35. (SFD 2014, Paris)

Feasibility of high convection volumes in on-line haemodiafiltration (HDF). Alain Ficheux, Nathalie Gayrard, Flore Duranton, Caroline Guzman, Ilan Szwarc, Johanna Bismuth-Mondolfo, Philippe Brunet, Marie-Françoise Servel and Àngel Argilés. Nephrology Dialysis Transplantation, Volume: 28, Supplement: 1, Pages: 211-211, Published: MAY 2013. (ERA-EDTA 2013, Istanbul)

Comparative study of 3p region in renal tumours showed that FHIT protein expression loss and not FHIT gene deletion would be specific for malignant cancers. Gayrard, Nathalie; Cacheux, Valere; Iborra, Francois; Mourad, Georges; Argiles, Angel. Nephrology Dialysis Transplantation, Volume: 21, Supplement: 4, Pages: 146-147, Published: JUL 2006. (ERA-EDTA 2006, Glasgow)


THESES

Natural history of chronic kidney disease : Analysis of pathophysiological and prognostic factors of renal failure and its complications, Flore Duranton, 2013

Chromosomal anomalies of renal tumors: study of the short arm of the 3rd chromosome, Nathalie Gayrard, 2006